An association between acute retinal necrosis syndrome and HLA-DQw7 and phenotype Bw62, DR4.

@article{Holland1989AnAB,
  title={An association between acute retinal necrosis syndrome and HLA-DQw7 and phenotype Bw62, DR4.},
  author={Gary Holland and Peter Jackson Cornell and Min Su Park and A A Barbetti and J. Yuge and Allan E. Kreiger and Henry J. Kaplan and Jay S. Pepose and John R. Heckenlively and William W. Culbertson},
  journal={American journal of ophthalmology},
  year={1989},
  volume={108 4},
  pages={370-4}
}
Human leukocyte antigen (HLA) typing was performed on 27 white patients with acute retinal necrosis syndrome. Antigens for the HLA-A, -B, -C, -DR and -DQ loci were determined, and frequencies were compared with racially matched controls. There was a statistically significant increase in the frequency of HLA-DQw7 (11 of 20 [55%] of patients vs 294 of 1546 [19%] of controls, P = .0004, relative risk 5.20) that remained significant at the P = .05 level when the P value was multiplied by the number… CONTINUE READING

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