An assessment of the risks of carcinogenicity associated with polyhydroxyalkanoates through an analysis of DNA aneuploid and telomerase activity.

@article{Peng2011AnAO,
  title={An assessment of the risks of carcinogenicity associated with polyhydroxyalkanoates through an analysis of DNA aneuploid and telomerase activity.},
  author={Si-wu Peng and Xiao-Yong Guo and Guan-Guan Shang and Jianhong Li and Xian-Yi Xu and Ming-Liang You and Ping Li and Guo-Qiang Chen},
  journal={Biomaterials},
  year={2011},
  volume={32 10},
  pages={2546-55}
}
Polyhydroxyalkanoates (PHA) are aliphatic polyesters synthesized by many bacteria. Because of their flexible mechanical strengths, superior elastic property, biodegradability and biocompatibility, PHA have been developed for applications as medical implants, drug delivery matrices, and devices to support cell growth. Lots of studies showed that PHA matrices improved cell proliferation and tissue regeneration. However, the possibility of whether rapid cell proliferation on PHA matrices will… CONTINUE READING