An assessment of the impact of incorporating time-of-flight information into clinical PET/CT imaging.

@article{Lois2010AnAO,
  title={An assessment of the impact of incorporating time-of-flight information into clinical PET/CT imaging.},
  author={Cristina Lois and Bjoern Jakoby and Misty J Long and K. F. Hubner and David W Barker and Michael E. Casey and Maurizio Conti and Vladimir Y. Panin and Dan J. Kadrmas and David W. Townsend},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2010},
  volume={51 2},
  pages={237-45}
}
The introduction of fast scintillators with good stopping power for 511-keV photons has renewed interest in time-of-flight (TOF) PET. The ability to measure the difference between the arrival times of a pair of photons originating from positron annihilation improves the image signal-to-noise ratio (SNR). The level of improvement depends upon the extent and distribution of the positron activity and the time resolution of the PET scanner. While specific estimates can be made for phantom imaging… CONTINUE READING