An assessment of the effects of internal neurolysis on a chronically compressed rat sciatic nerve.

Abstract

Chronically compressed nerves were treated with three surgical modalities. Simple decompression was compared to internal neurolysis with and without the addition of extrafascicular steroid. Electrophysiologic, histologic, and morphometric assessments were performed. Compressed control nerves demonstrated changes compatible with severe nerve compression (Wallerian degeneration). With simple decompression, improvement in histologic and electrophysiologic parameters occurred. When internal neurolysis was added to the decompression, further improvement in histologic and electrophysiologic parameters was noted. There was no added improvement with the addition of steroids.

0501002014201520162017
Citations per Year

98 Citations

Semantic Scholar estimates that this publication has 98 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Mackinnon1988AnAO, title={An assessment of the effects of internal neurolysis on a chronically compressed rat sciatic nerve.}, author={Susan E. Mackinnon and J P O'brien and Arnold Lee Dellon and A Robb McLean and Alan R Hudson and Daniel Hunter}, journal={Plastic and reconstructive surgery}, year={1988}, volume={81 2}, pages={251-8} }