An assessment of software solutions for the analysis of mass spectrometry based quantitative proteomics data.

@article{Mueller2008AnAO,
  title={An assessment of software solutions for the analysis of mass spectrometry based quantitative proteomics data.},
  author={Lukas N. Mueller and Mi-Youn K. Brusniak and D. R. Mani and Ruedi Aebersold},
  journal={Journal of proteome research},
  year={2008},
  volume={7 1},
  pages={51-61}
}
Over the past decade, a series of experimental strategies for mass spectrometry based quantitative proteomics and corresponding computational methodology for the processing of the resulting data have been generated. We provide here an overview of the main quantification principles and available software solutions for the analysis of data generated by liquid chromatography coupled to mass spectrometry (LC-MS). Three conceptually different methods to perform quantitative LC-MS experiments have… CONTINUE READING

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