An assessment of beclomethasone dipropionate clathrate formation in a model suspension metered dose inhaler.

Abstract

The aims of this study were to investigate and characterize the physico-chemical properties of beclomethasone dipropionate (BDP) crystallized from tricholoromonofluoromethane (CFC-11). Physical interactions in a model pressurised metered dose inhaler (pMDI) system and changes in surface energy after size reduction (micronization) were determined. Although… (More)
DOI: 10.1016/j.ijpharm.2010.02.024

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Cite this paper

@article{Bouhroum2010AnAO, title={An assessment of beclomethasone dipropionate clathrate formation in a model suspension metered dose inhaler.}, author={Abdennour Bouhroum and Jonathan C. Burley and Neil R Champness and Richard C Toon and Philip A Jinks and Philip M. Williams and Clive J. Roberts}, journal={International journal of pharmaceutics}, year={2010}, volume={391 1-2}, pages={98-106} }