An assay for the mannan-binding lectin pathway of complement activation.

@article{Petersen2001AnAF,
  title={An assay for the mannan-binding lectin pathway of complement activation.},
  author={Steen V Petersen and Steffen Thiel and Lisbeth Jensen and Rudi M Steffensen and Jens Christian Jensenius},
  journal={Journal of immunological methods},
  year={2001},
  volume={257 1-2},
  pages={107-16}
}
The mannan-binding lectin (MBL) pathway of complement activation has been established as the third pathway of complement activation. MBL is a carbohydrate-binding serum protein, which circulates in complex with serine proteases known as mannan-binding lectin associated serine proteases (MASPs). When bound to microorganisms, the MBL complex activates the complement components C4 and C2, thereby generating the C3 convertase and leading to opsonisation by the deposition of C4b and C3b fragments… CONTINUE READING

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