An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition.

@article{Stein2006AnAP,
  title={An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition.},
  author={Gary S Stein and Andre J van Wijnen and Janet L Stein and Jane B Lian and Mart{\'i}n A. Montecino and Sayyed K Zaidi and Corey D Braastad},
  journal={Journal of cellular physiology},
  year={2006},
  volume={209 3},
  pages={706-10}
}
A prominent role for the execution of cell cycle and growth regulatory mechanisms within the three-dimensional context of nuclear architecture is becoming increasingly evident. Signaling pathways and regulatory networks that govern activation and suppression of genes controlling proliferation are functionally integrated for the organization and assembly of transcriptional machinery in nuclear microenvironments. The transcriptional activation of histone genes at the G1/S phase transition (S… CONTINUE READING

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