An aptamer based competition assay for protein detection using CNT activated gold-interdigitated capacitor arrays.

@article{Qureshi2012AnAB,
  title={An aptamer based competition assay for protein detection using CNT activated gold-interdigitated capacitor arrays.},
  author={Anjum Qureshi and Irena Roci and Yasar Gurbuz and Javed H. Niazi},
  journal={Biosensors & bioelectronics},
  year={2012},
  volume={34 1},
  pages={165-70}
}
An aptamer can specifically bind to its target molecule, or hybridize with its complementary strand. A target bound aptamer complex has difficulty to hybridize with its complementary strand. It is possible to determine the concentration of target based on affinity separation system for the protein detection. Here, we exploited this property using C-reactive protein (CRP) specific RNA aptamers as probes that were immobilized by physical adsorption on carbon nanotubes (CNTs) activated gold… CONTINUE READING

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