An approach to understanding the transmission of Mycobacterium leprae using molecular and immunological methods: results from the MILEP2 study.

@article{Smith2004AnAT,
  title={An approach to understanding the transmission of Mycobacterium leprae using molecular and immunological methods: results from the MILEP2 study.},
  author={William Cairns S. Smith and Christine M Smith and Ian A Cree and Ruprendra S Jadhav and Murdo Macdonald and Vijay K Edward and Linda Oskam and Stella M van Beers and Paul R. Klatser},
  journal={International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association},
  year={2004},
  volume={72 3},
  pages={269-77}
}
BACKGROUND The current strategy for leprosy control using case detection and treatment has greatly reduced the prevalence of leprosy, but has had no demonstrable effect on interrupting transmission. METHODS Three leprosy endemic communities in India were recruited, examined, and followed up sequentially over 2 yrs using nasal swabs and saliva collections. The nasal swabs were tested by polymerase chain reaction for the presence of M. leprae and the saliva was assayed for anti-M. leprae IgA… CONTINUE READING

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