An approach to the immunophenotypic features of circulating CD4+NKG2D+ T cells in invasive cervical carcinoma

@inproceedings{GarcaChagolln2015AnAT,
  title={An approach to the immunophenotypic features of circulating CD4+NKG2D+ T cells in invasive cervical carcinoma},
  author={Mariel Garc{\'i}a-Chagoll{\'a}n and Luis Felipe Jave-Suarez and Jesse Haramati and Miriam Ruth Bueno-Topete and Adriana Aguilar-Lemarroy and Ciro Estrada-Ch{\'a}vez and Blanca Estela Bastidas-Ram{\'i}rez and Ana Laura Pereira-Su{\'a}rez and Susana del Toro-Arreola},
  booktitle={Journal of Biomedical Science},
  year={2015}
}
NKG2D, an activating immunoreceptor, is primarily restricted to NK cells and CD8+ T cells. The existence of an atypical cytotoxic CD4+NKG2D+ T cell population has also been found in patients with autoimmune dysfunctions. Nonetheless, contradictory evidence has categorized this population with a regulatory rather than cytotoxic role in other situations. These confounding data have led to the proposal that two distinct CD4+NKG2D+ T cell subsets might exist. The immune response elicited in… CONTINUE READING
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