An approach to identifying sequential metabolites of a typical phenylethanoid glycoside, echinacoside, based on liquid chromatography-ion trap-time of flight mass spectrometry analysis.

@article{Wang2009AnAT,
  title={An approach to identifying sequential metabolites of a typical phenylethanoid glycoside, echinacoside, based on liquid chromatography-ion trap-time of flight mass spectrometry analysis.},
  author={Yuxin Wang and Haiping Hao and Guang-ji Wang and Pengfei Tu and Yong Jiang and Yan Liang and Liang Dai and Hao Yang and Li Lai and Chaonan Zheng and Qiong Wang and Nan Cui and Yitong Liu},
  journal={Talanta},
  year={2009},
  volume={80 2},
  pages={572-80}
}
Metabolite identification for the compounds that undergo multiple and sequential metabolism is still a great challenge. Echinacoside (ECH), a typical phenylethanoid glycoside, contains multiple unstable chemical bonds and high reactive functional groups which are susceptible to multiple pathways of degradation and metabolism, leading great difficulties for its metabolite identification. This study proposed a novel approach for rapidly identifying the complicated and unpredictable metabolites of… CONTINUE READING