An approach to hyperolactone C and analogues using late stage conjugate addition on an oxonium ylide-derived spirofuranone.

@article{Hodgson2013AnAT,
  title={An approach to hyperolactone C and analogues using late stage conjugate addition on an oxonium ylide-derived spirofuranone.},
  author={D. Hodgson and Elena Moreno-Clavijo and S. Day and Stanislav Man},
  journal={Organic & biomolecular chemistry},
  year={2013},
  volume={11 32},
  pages={
          5362-9
        }
}
  • D. Hodgson, Elena Moreno-Clavijo, +1 author Stanislav Man
  • Published 2013
  • Chemistry, Medicine
  • Organic & biomolecular chemistry
  • A stereocontrolled synthesis of norphenyl hyperolactone C together with its utility as a direct precursor to the anti-HIV agent hyperolactone C and analogues by addition of organolithiums, are described. Preliminary studies to access this key building block in a catalytic enantioselective manner are also reported. 
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    Oxonium Ylide Rearrangements in Synthesis
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