An antiviral T-Cell clone defines a functional supertypic specificity shared by different HLA-DR molecules from DR2-short, DRw11, and DRwl3 Haplotypes

Abstract

An influenza virus-specific HLA class IIrestricted human T4+ clone (Ij) allows us to define a new functional supertypic HLA class II specificity shared by three different haplotypes. Influenza A virus-infected antigen-presenting cells of these three haplotypes, HLA-DR2 short, DRw11, and DRw13, are able to stimulate Ij cells. The same precise viral… (More)
DOI: 10.1007/BF00364272

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