An antiserum against Atlantic salmon IFNa1 detects IFN and neutralizes antiviral activity produced by poly I:C stimulated cells.

@article{Berg2009AnAA,
  title={An antiserum against Atlantic salmon IFNa1 detects IFN and neutralizes antiviral activity produced by poly I:C stimulated cells.},
  author={Kristel Berg and Tina Svingerud and Baojian Sun and B\orre Robertsen},
  journal={Developmental and comparative immunology},
  year={2009},
  volume={33 4},
  pages={638-45}
}
Type I interferons (IFNs) play a crucial role in innate immune responses against virus infections in vertebrates. Two IFNs (IFNa1 and IFNa2) have previously been cloned from Atlantic salmon. In the present work a polyclonal antiserum, which was generated against salmon IFNa1 was used to study its production in cells by immunoblot detection and… CONTINUE READING