An antiinflammatory effect of salmeterol, a long-acting beta(2) agonist, assessed in airway biopsies and bronchoalveolar lavage in asthma.

@article{Li1999AnAE,
  title={An antiinflammatory effect of salmeterol, a long-acting beta(2) agonist, assessed in airway biopsies and bronchoalveolar lavage in asthma.},
  author={Xiu-min Li and C. Ward and Frank Thien and Randy Bish and Terry Bamford and X Bao and Michelle Bailey and John Wilson and Eugene Haydn Walters},
  journal={American journal of respiratory and critical care medicine},
  year={1999},
  volume={160 5 Pt 1},
  pages={1493-9}
}
The addition of long-acting beta(2) agonists to inhaled corticosteroid (ICS) therapy in symptomatic patients with asthma improves clinical status more than increasing the dose of ICS. It has been suggested that these benefits could be at the cost of an increase in airway inflammation, but few histopathological studies have been performed in the relevant group. In a double-blind, parallel-group, placebo-controlled study, we randomly assigned 50 symptomatic patients with asthma who were receiving… CONTINUE READING