An antigen receptor (NCCRP-1) on nonspecific cytotoxic cells is a phosphoprotein associated with the JAK-STAT activation pathway.

@article{Evans1999AnAR,
  title={An antigen receptor (NCCRP-1) on nonspecific cytotoxic cells is a phosphoprotein associated with the JAK-STAT activation pathway.},
  author={Donald Lee Evans and John H. Leary and Liliana Jaso-Friedmann},
  journal={Cellular signalling},
  year={1999},
  volume={11 4},
  pages={287-92}
}
The antigen receptor (nonspecific cytotoxic cell receptor protein-1/NCCRP-1) on nonspecific cytotoxic cells (NCC) is a 32-kDa predicted Type III membrane protein. The N-terminal cytoplasmic portion of this receptor contains full length and truncated BOX-1 motifs. These motifs are also found on cytokine, erythropoietin and growth hormone receptors and provide docking sites for JAK kinases. In the present study, we investigated a relationship between NCCRP-1 and JAK2 kinase binding. A possible… CONTINUE READING