An anticoagulant fucan sulfate with hexasaccharide repeating units from the sea cucumber Holothuria albiventer.

@article{Cai2018AnAF,
  title={An anticoagulant fucan sulfate with hexasaccharide repeating units from the sea cucumber Holothuria albiventer.},
  author={Ying Cai and Wenjiao Yang and Ronghua Yin and Lutan Zhou and Zhongkun Li and Mingyi Wu and Jinhua Zhao},
  journal={Carbohydrate research},
  year={2018},
  volume={464},
  pages={
          12-18
        }
}
A fucan sulfate was isolated and purified from the sea cucumber Holothuria albiventer by papain enzymolysis, alkaline hydrolysis and ion-exchange chromatography. The water-soluble polysaccharide had high molecular weight and contained fucose and sulfate in a molar ratio of about 1:0.83. Methylation analysis of the native polysaccharide indicated that its glycosidic linkages and sulfate substituents might be at O-3 or O-3, 4 or O-2, 3, or O-2, 3, 4 positions. FT-IR and 2D NMR spectroscopies… CONTINUE READING
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