An animal model of cerebral infarction. Homologous blood clot emboli in rats.

  title={An animal model of cerebral infarction. Homologous blood clot emboli in rats.},
  author={Minako Kudo and Akinori Aoyama and S Ichimori and Nami Fukunaga},
  volume={13 4},
An experimental model of cerebral infarction is created in rats by intracarotid injection of their homologous blood clots. This is the first small animal model in which embolization was achieved by homologous blood clots. The infarcts were produced predominantly in the territory of the middle cerebral artery. The low mortality rate and excellent reproduction rate make possible the correlative study of morphological, biochemical, and metabolic parameters at selected points in time to reconstruct… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 60 extracted citations

Different strokes for different folks: the rich diversity of animal models of focal cerebral ischemia.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2010
View 7 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 13 references

Experimental embolic stroke in the guinea pig (Cuvis cobaya).

Journal of neuropathology and experimental neurology • 1980

Morphological validation of ischemic stroke models

J Moossy
Acta Neuropathol • 1979

during the early stage of development of cerebral infarction

GF Molinari, JP Laurent

Similar Papers

Loading similar papers…