An animal model for low dose ethanol-induced locomotor stimulation: behavioral characteristics.

@article{Erickson1985AnAM,
  title={An animal model for low dose ethanol-induced locomotor stimulation: behavioral characteristics.},
  author={Carlton K. Erickson and A Kochhar},
  journal={Alcoholism, clinical and experimental research},
  year={1985},
  volume={9 4},
  pages={
          310-4
        }
}
The present paper describes a rat strain, Maudsley reactive (MR/N), which dramatically and reliably shows enhanced locomotor stimulation in an openfield apparatus after low doses of ethanol. Other strains, Sprague-Dawley and Wistar inbred, do not show stimulation, whereas Maudsley nonreactive rats show a less dramatic and variable response to ethanol, compared to the MR/N strain. Female MR/N rats show greater stimulation than male MR/N rats, and the response is dose-, age-, and apparatus… CONTINUE READING

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