An ancestral mitochondrial DNA resembling a eubacterial genome in miniature
@article{Lang1997AnAM, title={An ancestral mitochondrial DNA resembling a eubacterial genome in miniature}, author={B. F. Lang and G. Burger and C. O'kelly and R. Cedergren and G. Golding and C. Lemieux and D. Sankoff and M. Turmel and M. Gray}, journal={Nature}, year={1997}, volume={387}, pages={493-497} }
Mitochondria, organelles specialized in energy conservation reactions in eukaryotic cells, have evolved from eubacteria-like endo-symbionts 1–3 whose closest known relatives are the rickettsial group of α-proteobacteria 4,5. Because characterized mitochondrial genomes vary markedly in structure3, it has been impossible to infer from them the initial form of the proto-mitochondrial genome. This would require the identification of minimally derived mitochondrial DNAs that better reflect the… CONTINUE READING
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