An analysis of high-risk human papillomavirus DNA-negative cervical precancers in the ASCUS-LSIL Triage Study (ALTS).

@article{Castle2008AnAO,
  title={An analysis of high-risk human papillomavirus DNA-negative cervical precancers in the ASCUS-LSIL Triage Study (ALTS).},
  author={Philip E Castle and John Thomas Cox and Jose A. Jeronimo and Diane Macht Solomon and Cosette Marie Therese. Wheeler and Patti Gravitt and Mark Schiffman},
  journal={Obstetrics and gynecology},
  year={2008},
  volume={111 4},
  pages={
          847-56
        }
}
OBJECTIVE To describe women diagnosed with cervical intraepithelial neoplasia-grade 3 (CIN-3) diagnosed over the 2-year duration of the atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intraepithelial lesion (LSIL) Triage Study (ALTS) that tested negative for high-risk human papillomavirus (HPV) at enrollment. METHODS Clinical center pathologists and quality control pathology group reviewed all histology; any CIN-3 diagnosis on biopsy or loop electrosurgical… CONTINUE READING
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