An amino-acid taste receptor
@article{Nelson2002AnAT, title={An amino-acid taste receptor}, author={G. Nelson and J. Chandrashekar and Mark A. Hoon and L. Feng and Grace Zhao and N. Ryba and C. Zuker}, journal={Nature}, year={2002}, volume={416}, pages={199-202} }
The sense of taste provides animals with valuable information about the nature and quality of food. Mammals can recognize and respond to a diverse repertoire of chemical entities, including sugars, salts, acids and a wide range of toxic substances. Several amino acids taste sweet or delicious (umami) to humans, and are attractive to rodents and other animals. This is noteworthy because l-amino acids function as the building blocks of proteins, as biosynthetic precursors of many biologically… CONTINUE READING
Paper Mentions
1,159 Citations
L-Amino Acids Elicit Diverse Response Patterns in Taste Sensory Cells: A Role for Multiple Receptors
- Biology, Medicine
- PloS one
- 2015
- 21
- Highly Influenced
- PDF
Receptors for the detection of L-amino acids and IMP by mouse taste sensory cells
- Chemistry
- 2016
- Highly Influenced
Involvement of the Calcium-sensing Receptor in Human Taste Perception
- Medicine, Biology
- The Journal of Biological Chemistry
- 2009
- 164
- PDF
Taste receptors for umami: the case for multiple receptors.
- Biology, Medicine
- The American journal of clinical nutrition
- 2009
- 147
- PDF
Structural basis for perception of diverse chemical substances by T1r taste receptors
- Biology, Medicine
- Nature communications
- 2017
- 40
- PDF
References
SHOWING 1-10 OF 42 REFERENCES
A metabotropic glutamate receptor variant functions as a taste receptor
- Biology, Medicine
- Nature Neuroscience
- 2000
- 513
- PDF
Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac
- Biology, Medicine
- Nature Genetics
- 2001
- 444
Putative Mammalian Taste Receptors A Class of Taste-Specific GPCRs with Distinct Topographic Selectivity
- Biology, Medicine
- Cell
- 1999
- 618
- PDF
Identification of a novel member of the T1R family of putative taste receptors
- Biology, Medicine
- Journal of neurochemistry
- 2001
- 279