An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA

  title={An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA},
  author={L. Chow and R. Gelinas and T. Broker and R. Roberts},
  • L. Chow, R. Gelinas, +1 author R. Roberts
  • Published 1977
  • Biology, Medicine
  • Cell
  • The 5' terminal sequences of several adenovirus 2 (Ad2) mRNAs, isolated late in infection, are complementary to sequences within the Ad2 genome which are remote from the DNA from which the main coding sequence of each mRNA is transcribed. [...] Key Result The 5' terminal sequences of mRNAs in R loops, variously located between positions 36 and 92, form complex secondary hybrids with single-stranded DNA from restriction endonuclease fragments containing sequences to the left of position 36 on the Ad2 genome.Expand Abstract
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