An alternative respiratory pathway on Candida krusei: implications on susceptibility profile and oxidative stress.

@article{CostadeOliveira2012AnAR,
  title={An alternative respiratory pathway on Candida krusei: implications on susceptibility profile and oxidative stress.},
  author={Sofia Costa-de-Oliveira and Bel{\'e}m Sampaio-Marques and Matilde Barbosa and E. T. A. Ricardo and Cid{\'a}lia Pina-Vaz and Paula Ludovico and Ac{\'a}cio Agostinho Gonçalves Rodrigues},
  journal={FEMS yeast research},
  year={2012},
  volume={12 4},
  pages={423-9}
}
Our aim was to detect the presence of an alternative oxidase (AOX) in Candida krusei clinical strains and its influence on fluconazole susceptibility and in reactive oxygen species (ROS) production. Candida krusei clinical isolates were tested to evaluate the presence of AOX. Debaromyces hansenii 2968 (AOX positive) and Saccharomyces cerevisiae BY4742 (AOX negative) were used as control strains. Measurements of oxygen consumption were performed in the presence of 1 mM KCN, an inhibitor of the… CONTINUE READING
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