An alternative, nonapoptotic form of programmed cell death.

@article{Sperandio2000AnAN,
  title={An alternative, nonapoptotic form of programmed cell death.},
  author={Sabina Sperandio and Ian de Belle and Dale E. Bredesen},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2000},
  volume={97 26},
  pages={14376-81}
}
The term apoptosis often has been used interchangeably with the term programmed cell death. Here we describe a form of programmed cell death that is distinct from apoptosis by the criteria of morphology, biochemistry, and response to apoptosis inhibitors. Morphologically, this alternative form of programmed cell death appears during development and in some cases of neurodegeneration. Despite its lack of response to caspase inhibitors and Bcl-x(L), we show that this form of cell death is driven… CONTINUE READING
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Electron Microscopy (Jones and Bartlett, Boston)

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