An alteration in the phosphorylation of vimentin-type intermediate filaments is associated with mitosis in cultured mammalian cells.

@article{Evans1982AnAI,
  title={An alteration in the phosphorylation of vimentin-type intermediate filaments is associated with mitosis in cultured mammalian cells.},
  author={Ronald M Evans and Louis M. Fink},
  journal={Cell},
  year={1982},
  volume={29 1},
  pages={43-52}
}
Analysis of cultured Chinese hamster ovary (CHO) cells has shown that vimentin exists primarily as two 57,000 dalton isoelectric variants, a nonphosphorylated form and a slightly more acidic phosphorylated form. Similar analyses of CHO cells that were treated with colcemid show the presence of at least two to three additional, more acidic, phosphorylated vimentin isoelectric variants. An increasing 32P-specific activity of these variants suggests that this alteration involves increased… CONTINUE READING

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