FamSeq: A Variant Calling Program for Family-Based Sequencing Data Using Graphics Processing Units
This paper presents a recursive algorithm to approximate the likelihood in arbitrary pedigrees with loops. The algorithm handles any number and nesting levels of loops in pedigrees. The loops are cut as described in a previous publication and the approximate likelihood is simultaneously computed using the cut pedigree. No identification of a loop in the pedigree is necessary before the algorithm is applied.