An aging Interventions Testing Program: study design and interim report

@article{Miller2007AnAI,
  title={An aging Interventions Testing Program: study design and interim report},
  author={Richard A. Miller and D. Harrison and C. M. Astle and R. Floyd and K. Flurkey and K. Hensley and M. Javors and C. Leeuwenburgh and J. Nelson and E. Ongini and N. Nadon and H. Warner and R. Strong},
  journal={Aging Cell},
  year={2007},
  volume={6}
}
The National Institute on Aging's Interventions Testing Program (ITP) has developed a plan to evaluate agents that are considered plausible candidates for delaying rates of aging. Key features include: (i) use of genetically heterogeneous mice (a standardized four‐way cross), (ii) replication at three test sites (the Jackson Laboratory, TJL; University of Michigan, UM; and University of Texas, UT), (iii) sufficient statistical power to detect 10% changes in lifespan, (iv) tests for age… Expand
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