An aging Interventions Testing Program: study design and interim report

@article{Miller2007AnAI,
  title={An aging Interventions Testing Program: study design and interim report},
  author={Richard A. Miller and David E Harrison and Clinton M. Astle and Robert A. Floyd and Kevin Flurkey and Kenneth L. Hensley and Martin A. Javors and Christiaan Leeuwenburgh and James F. Nelson and Ennio Ongini and Nancy L. Nadon and Huber R. Warner and Randy Strong},
  journal={Aging Cell},
  year={2007},
  volume={6}
}
The National Institute on Aging's Interventions Testing Program (ITP) has developed a plan to evaluate agents that are considered plausible candidates for delaying rates of aging. Key features include: (i) use of genetically heterogeneous mice (a standardized four‐way cross), (ii) replication at three test sites (the Jackson Laboratory, TJL; University of Michigan, UM; and University of Texas, UT), (iii) sufficient statistical power to detect 10% changes in lifespan, (iv) tests for age… 

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