An adenovirus glycoprotein binds heavy chains of class I transplantation antigens from man and mouse

@article{Signs1982AnAG,
  title={An adenovirus glycoprotein binds heavy chains of class I transplantation antigens from man and mouse},
  author={Christer Sign{\"a}s and Michael G. Katze and H{\aa}kan Persson and L. Philipson},
  journal={Nature},
  year={1982},
  volume={299},
  pages={175-178}
}
The successful killing of virus-infected cells by cytotoxic T lymphocytes (CTL) is dependent on the recognition of both a viral product and class I antigens of the major histocompatibility complex (MHC) on the infected cell surface1–9. Whether these two entities are found independently on the cell surface and therefore recognized by two different CTL receptors, or whether they are associated together and can therefore be recognized by a single receptor is not known10. The association between an… CONTINUE READING
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