An active precursor in assembly of yeast nuclear ribonuclease P.

@article{Srisawat2002AnAP,
  title={An active precursor in assembly of yeast nuclear ribonuclease P.},
  author={Chatchawan Srisawat and Felicia Houser-Scott and Edouard Bertrand and Shaohua Xiao and Robert H Singer and David Engelke},
  journal={RNA},
  year={2002},
  volume={8 10},
  pages={1348-60}
}
The RNA-protein subunit assembly of nuclear RNase P was investigated by specific isolation and characterization of the precursor and mature forms of RNase P using an RNA affinity ligand. Pre-RNase P was as active in pre-tRNA cleavage as mature RNase P, although it contained only seven of the nine proteins found in mature RNase P. Pop3p and Rpr2p were not required for maturation of the RPR1 RNA subunit and virtually absent from pre-RNase P, implying that they are dispensable for pre-tRNA… CONTINUE READING