An accurate, clinically feasible multi-gene expression assay for predicting metastasis in uveal melanoma.

@article{Onken2010AnAC,
  title={An accurate, clinically feasible multi-gene expression assay for predicting metastasis in uveal melanoma.},
  author={Michael D Onken and Lori A. Worley and Meghan D Tuscan and J. William Harbour},
  journal={The Journal of molecular diagnostics : JMD},
  year={2010},
  volume={12 4},
  pages={
          461-8
        }
}
Uveal (ocular) melanoma is an aggressive cancer that often forms undetectable micrometastases before diagnosis of the primary tumor. These micrometastases later multiply to generate metastatic tumors that are resistant to therapy and are uniformly fatal. We have previously identified a gene expression profile derived from the primary tumor that is extremely accurate for identifying patients at high risk of metastatic disease. Development of a practical clinically feasible platform for analyzing… CONTINUE READING

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