An accumulative site-specific gene integration system using Cre recombinase-mediated cassette exchange.

Abstract

The Cre-loxP system is frequently used for site-specific recombination in animal cells. The equilibrium and specificity of the recombination reaction can be controlled using mutated loxPs. In the present study, we designed an accumulative site-specific gene integration system using Cre recombinase and mutated loxPs in which the Cre-mediated cassette… (More)
DOI: 10.1002/bit.22619

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@article{Kameyama2010AnAS, title={An accumulative site-specific gene integration system using Cre recombinase-mediated cassette exchange.}, author={Yujiro Kameyama and Yoshinori Kawabe and Akira Ito and Masamichi Kamihira}, journal={Biotechnology and bioengineering}, year={2010}, volume={105 6}, pages={1106-14} }