An Update on the Structure of Oxazolidinone Analogs and a Comparison with Linezolid in Terms of In Vitro and Intracellular Efficacy against Clinically Relevant Bacterial Species.

Abstract

Oxazolidinones constitute a novel class of antimicrobials as inhibitors of bacterial ribosomal protein synthesis. In this study, we identified 15 novel oxazolidinone analogs with potent antituberculosis activities. Compounds sy124 and sy125 showed the best activity in vitro (better than that of the linezolid) against various clinically relevant bacterial… (More)
DOI: 10.7883/yoken.JJID.2017.104

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Cite this paper

@article{Tang2017AnUO, title={An Update on the Structure of Oxazolidinone Analogs and a Comparison with Linezolid in Terms of In Vitro and Intracellular Efficacy against Clinically Relevant Bacterial Species.}, author={Qian Tang and Yanfang Zhao and Boxuan Xu and Ping Gong and Di Wang}, journal={Japanese journal of infectious diseases}, year={2017}, volume={70 6}, pages={678-681} }