An Update on the Pathophysiology of Complex Regional Pain Syndrome

  title={An Update on the Pathophysiology of Complex Regional Pain Syndrome},
  author={Stephen Bruehl},
  • S. Bruehl
  • Published 1 September 2010
  • Medicine, Psychology, Biology
  • Anesthesiology
Complex regional pain syndrome (CRPS) is a neuropathic pain disorder with significant autonomic features. Few treatments have proven effective, in part, because of a historically poor understanding of the mechanisms underlying the disorder. CRPS research largely conducted during the past decade has substantially increased knowledge regarding its pathophysiologic mechanisms, indicating that they are multifactorial. Both peripheral and central nervous system mechanisms are involved. These include… 

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