An Update on Non‐Pharmacological Neuromodulation for the Acute and Preventive Treatment of Migraine

@article{Puledda2017AnUO,
  title={An Update on Non‐Pharmacological Neuromodulation for the Acute and Preventive Treatment of Migraine},
  author={Francesca Puledda and Peter J. Goadsby},
  journal={Headache: The Journal of Head and Face Pain},
  year={2017},
  volume={57}
}
  • F. PuleddaP. Goadsby
  • Published 1 April 2017
  • Medicine, Psychology
  • Headache: The Journal of Head and Face Pain
To review current neuromodulation treatments available for migraine therapy, both in the acute and preventive setting. 

Remote Electrical Neuromodulation (REN) Relieves Acute Migraine: A Randomized, Double‐Blind, Placebo‐Controlled, Multicenter Trial

To assess the efficacy and safety of a remote electrical neuromodulation (REN) device for the acute treatment of migraine, a large number of patients were referred for treatment with a single device.

Current Prophylactic Medications for Migraine and Their Potential Mechanisms of Action

A relatively high number of different medications used for migraine prevention in clinical practice differ in their mechanisms of action, but some general themes can be identified from the mechanisms at play.

Neuromodulation for the Acute and Preventive Therapy of Migraine and Cluster Headache

This review focuses on neuromodulation devices that have been studied for migraine and cluster headache, with special attention to those that have gained food and drug administration clearance and how these devices can be used in patients who might have limited pharmacologic options.

Review of evidence on noninvasive vagus nerve stimulation for treatment of migraine: efficacy, safety, and implications.

GammaCore treatment is both safe and effective as an acute treatment for migraine and provides substantial value to patients and to payers for consideration for pay-for-performance health coverage strategies and policies.

Emerging Treatments in Episodic Migraine

A number of new medications are emerging for the acute and preventive treatment of migraine, including CGRP monoclonal antibodies, C GRP receptor antagonists, serotonin 5-HT1F agonists, and PACAP receptor monoc Lonal antibodies.

Complementary and Integrative Medicine for Neurological Conditions: A Review

The use of selected, evidence based CAM therapies for the prevention and treatment of migraine, carpal tunnel syndrome, and dementia are presented.

A COMPREHENSIVE STUDY ON NERIVIO MIGRA

There is a great unmet need for alternative acute migraine treatments that are both effective and well tolerated and non-invasive neuromodulation is safe, well tolerated, and may have fewer adverse effects than drugs.

Comment: Noninvasive neurostimulation for migraine should be part of the general neurologist's therapeutic armamentarium

The PRESTO study adds to the evidence that noninvasive vagus nerve stimulation is an effective acute treatment for migraine by producing higher pain-free rates than sham stimulation 30 minutes and 1 hour post-treatment.

Preventive Migraine Treatment

  • R. Burch
  • Medicine, Psychology
    Continuum
  • 2021
Many pharmacologic and nonpharmacologic treatment options are available for the prevention of migraine, including newer therapies aimed at the CGRP pathway as well as older treatments with good evidence for efficacy.

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