An Under-Recognized Benefit of Cardiopulmonary Resuscitation: Organ Transplantation*

@article{Orioles2013AnUB,
  title={An Under-Recognized Benefit of Cardiopulmonary Resuscitation: Organ Transplantation*},
  author={Alberto Orioles and Wynne Ellen Morrison and Joseph W. Rossano and Paul M. Shore and Richard Hasz and Amy C Martiner and Robert A. Berg and Vinay M. Nadkarni},
  journal={Critical Care Medicine},
  year={2013},
  volume={41},
  pages={2794–2799}
}
Objective:For many patients who suffer cardiac arrest, cardiopulmonary resuscitation does not result in long-term survival. For some of these patients, the evolution to donation of organs becomes an option. Organ transplantation after cardiopulmonary resuscitation is not reported as an outcome of cardiopulmonary resuscitation and is therefore overlooked. We sought to determine the number and proportion of organs transplanted from donors who received cardiopulmonary resuscitation after a cardiac… 

Cardiopulmonary resuscitation: saving life then saving organs?

The message for critical care practitioners is that despite the theoretical potential to worsen ischemic organ injury, the provision of CPR does not necessarily preclude organ donation or impair transplant graft function, and should encourage clinicians to attempt CPR with the goal of preserving the opportunity for organ donation.

Impact of donor cardiopulmonary resuscitation on the outcome of simultaneous pancreas–kidney transplantation—a retrospective study

It is indicated that post‐CPR brain‐dead donors are suitable for PT without increasing the risk of complications, and no statistically significant association between donor CPR and patient or graft survival is suggested.

Cardiopulmonary Resuscitation Maneuvers in the Organ and Tissue Donor Patient

The scientific evidence postulates mainly a benefit of the cardiopulmonary resuscitation maneuvers in the donor patient, without involvement in the organs because it increases their Blood perfusion and their oxygenation.

Organ donation after out-of-hospital cardiac arrest: a population-based study of data from the Paris Sudden Death Expertise Center

Patients with OHCA constitute a valuable source of donated organs, and special attention should be paid to young patients withOHCA of neurological cause.

Cardio‐pulmonary resuscitation of brain‐dead organ donors: a literature review and suggestions for practice

It is concluded that OP‐CPR can benefit patients and families by fulfilling the wish to donate, however, it is an aggressive procedure that can cause physical damage to patients, and risks psychological harm to families and healthcare professionals.

The rate of brain death and organ donation in patients resuscitated from cardiac arrest: a systematic review and meta-analysis

In patients with hypoxic-ischaemic brain injury following CPR, more than 10% of deaths were due to brain death, and more than 40 % of brain-dead patients could donate organs, suggesting patients who are unconscious after resuscitation from cardiac arrest, especially when resuscitated using e-CPR, should be carefully screened for signs of brain death.

Brain-Dead Donors on Extracorporeal Membrane Oxygenation*

Brain-dead patients with ongoing extracorporeal membrane oxygenation are suitable for organ procurement, and they have more severe medical conditions than those without extracorporation, according to a retrospective analysis of the national information system.

Treating the donor

Care of patients with catastrophic brain injury incorporating supportive therapy targeted at specific goals and delivered by experienced specialists provides the best donation outcomes and pathways represent best practice critical care applied to this population.

A simplified preservation method for lungs donated after cardiac death.

...

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