An Unbiased Analysis Method to Quantify mRNA Localization Reveals Its Correlation with Cell Motility

@inproceedings{Park2012AnUA,
  title={An Unbiased Analysis Method to Quantify mRNA Localization Reveals Its Correlation with Cell Motility},
  author={Hye Yoon Park and Tatjana Trcek and Amber L. Wells and Jeffrey A. Chao and Robert H Singer},
  booktitle={Cell reports},
  year={2012}
}
Localization of mRNA is a critical mechanism used by a large fraction of transcripts to restrict its translation to specific cellular regions. Although current high-resolution imaging techniques provide ample information, the analysis methods for localization have either been qualitative or employed quantification in nonrandomly selected regions of interest… CONTINUE READING