An UPLC-MS/MS Method for Simultaneous Quantification of the Components of Shenyanyihao Oral Solution in Rat Plasma

  title={An UPLC-MS/MS Method for Simultaneous Quantification of the Components of Shenyanyihao Oral Solution in Rat Plasma},
  author={Chunbo Jiang and Guoqiang Liang and Yan Ren and Tianjun Xu and Yongliang Song and Weimin Jin},
  journal={BioMed Research International},
Objectives To study the quantification of the components in rat plasma after oral administration of Shenyanyihao oral solution. Methods Shenyanyihao oral solution has been traditionally used for the treatments of chronic nephritis in clinics. Stachydrine, Danshensu, chlorogenic acid, protocatechuic acid, plantamajoside, aesculetin, isoquercitrin, ferulic acid, baicalin, and baicalein are regarded as the main compounds in Shenyanyihao oral solution. A sensitive, efficient, and precise UPLC-MS/MS… 

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