An SCF-like ubiquitin ligase complex that controls presynaptic differentiation

@article{Liao2004AnSU,
  title={An SCF-like ubiquitin ligase complex that controls presynaptic differentiation},
  author={Edward H Liao and Wesley Hung and Benjamin S Abrams and Mei Zhen},
  journal={Nature},
  year={2004},
  volume={430},
  pages={345-350}
}
During synapse formation, specialized subcellular structures develop at synaptic junctions in a tightly regulated fashion. Cross-signalling initiated by ephrins, Wnts and transforming growth factor-β family members between presynaptic and postsynaptic termini are proposed to govern synapse formation. It is not well understood how multiple signals are integrated and regulated by developing synaptic termini to control synaptic differentiation. Here we report the identification of FSN-1, a novel F… 
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