An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration.


Adult stem cells sustain tissue maintenance and regeneration throughout the lifetime of an animal. These cells often reside in specific signalling niches that orchestrate the stem cell's balancing act between quiescence and cell-cycle re-entry based on the demand for tissue regeneration. How stem cells maintain their capacity to replenish themselves after… (More)
DOI: 10.1038/nature10940


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