Corpus ID: 6153302

An RNA-Seq screen of the dithiothreitol-induced apoptosis response in chicken cardiomyocytes

@inproceedings{Wan2017AnRS,
  title={An RNA-Seq screen of the dithiothreitol-induced apoptosis response in chicken cardiomyocytes},
  author={Chunyun Wan and Jinmei Xiang and Rui Guo and Shijin Yang and Youwen Li and Dingzong Guo},
  year={2017}
}
Cardiomyocytes in postnatal heart are terminally differentiated and thus possess limited capacity to regenerate. Loss of cardiomyocytes through apoptosis and necrosis can lead to heart failure and other serious consequences. Compared to mammals, substantially less research has been conducted on chicken cardiomyocytes; thus, the apoptosis pathways and many relevant genes remain unknown. To elucidate the pathways and genes involved in chicken myocardial cell apoptosis, primary cultures of chicken… Expand
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