An R package for analysis of whole-genome association studies.

@article{Clayton2007AnRP,
  title={An R package for analysis of whole-genome association studies.},
  author={David G. Clayton and Hin-Tak Leung},
  journal={Human heredity},
  year={2007},
  volume={64 1},
  pages={
          45-51
        }
}
OBJECTIVE To provide data classes and methods to facilitate the analysis of whole genome association studies in the R language for statistical computing. METHODS We have implemented data classes in which each genotype call is stored as a single byte. At this density, data for single chromosomes derived from large studies and new high-throughput gene chip platforms can be handled in memory. We use the object-oriented programming model introduced with version 4 of the S-plus package, usually… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 19 REFERENCES

Haploview: analysis an d visualization of ld and haplotype maps. Bioinformatics 2004;21:263–265

J CBarrett, B Fry, J Maller, M JDaly
  • 2004
VIEW 1 EXCERPT

Detecting disea se associations due to linkage disequilibrium using haplotype tags: A class of tests and the determinants of statistical power. Human Heredity 2003;56:18–31

J MChapman, J DCooper, J ATodd, D GClayton
  • 2003
VIEW 1 EXCERPT

The International H pMap project

B Fry, J Maller
  • Nature December
  • 2003