An Overview of the Introns-First Theory

  title={An Overview of the Introns-First Theory},
  author={David Penny and Marc P. Hoeppner and Anthony M. Poole and Daniel C. Jeffares},
  journal={Journal of Molecular Evolution},
We review the introns-first hypothesis a decade after it was first proposed. It is that exons emerged from non-coding regions interspersed between RNA genes in an early RNA world, and is a subcomponent of a more general ‘RNA-continuity’ hypothesis. The latter is that some RNA-based systems, especially in RNA processing, are ‘relics’ that can be traced back either to the RNA world that preceded both DNA and encoded protein synthesis or to the later ribonucleoprotein (RNP) world (before DNA took… 
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9 Introns and the RNA World
The RNA World is a hypothesis about the origin of life based on the view that the most critical event is the emergence of a self-replicating molecule, a molecule that can both copy itself and mutate
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The RNA World is a hypothesis about the origin of life based on the view that the most critical event is the emergence of a self-replicating molecule , a molecule that can both copy itself and mutate
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