An Optimized Individual Target Brain in the Talairach Coordinate System

  title={An Optimized Individual Target Brain in the Talairach Coordinate System},
  author={Peter V. Kochunov and Jack L. Lancaster and Paul M. Thompson and Arthur W. Toga and P. Brewer and L. J. Hardies and Peter T. Fox},
The goal of regional spatial normalization is to remove anatomical differences between individual three-dimensional brain images by warping them to match features of a single target brain. Current target brains are either an average, suitable for low-resolution brain mapping studies, or a single brain. While a single high-resolution target brain is desirable to match anatomical detail, it can lead to bias in anatomical studies. An optimization method to reduce the individual anatomical bias of… 

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