An Open-Label Study of Controlled-Release Melatonin in Treatment of Sleep Disorders in Children with Autism

@article{Giannotti2006AnOS,
  title={An Open-Label Study of Controlled-Release Melatonin in Treatment of Sleep Disorders in Children with Autism},
  author={Flavia Giannotti and Flavia Cortesi and Antonella Cerquiglini and Paola Bernabei},
  journal={Journal of Autism and Developmental Disorders},
  year={2006},
  volume={36},
  pages={741-752}
}
Long-term effectiveness of controlled-release melatonin in 25 children, aged 2.6–9.6 years with autism without other coexistent pathologies was evaluated openly. Sleep patterns were studied using Children’s Sleep Habits Questionnaire (CSHQ) and sleep diaries at baseline, after 1–3–6 months melatonin treatment and 1 month after discontinuation. Sleep diary and CSHQ showed a more problematic sleep in autistic children compared with controls. During treatment sleep patterns of all children… CONTINUE READING

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