An NF-κB–Dependent Role for JunB in the Induction of Proinflammatory Cytokines in LPS-Activated Bone Marrow–Derived Dendritic Cells

@inproceedings{Gomard2010AnNR,
  title={An NF-κB–Dependent Role for JunB in the Induction of Proinflammatory Cytokines in LPS-Activated Bone Marrow–Derived Dendritic Cells},
  author={Tiphanie Gomard and H. Michaud and Denis Temp{\'e} and Kevin Thiolon and M. Gasc{\'o}n Pelegr{\'i}n and Marc Piechaczyk},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Dendritic cells (DCs) play a key role in the induction of adaptive and memory immune responses. Upon encounter with pathogens, they undergo a complex maturation process and migrate toward lymphoid organs where they stimulate immune effector cells. This process is associated with dramatic transcriptome changes, pointing to a paramount role for transcription factors in DC activation and function. The regulation and the role of these transcription factors are however ill-defined and… CONTINUE READING

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