An LC-MS-MS method for the determination of nevirapine, a non-nucleoside reverse transcriptase inhibitor, in human plasma.

Abstract

A sensitive and rapid liquid chromatography tandem mass spectrometry (LC-MS-MS) method has been developed to measure the levels of the HIV-1 non-nucleoside reverse transcriptase inhibitor nevirapine (NVP) in human plasma. The analyte and internal standard (IS) are isolated from plasma by a simple perchloric acid precipitation of plasma proteins followed by… (More)

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@article{Chi2003AnLM, title={An LC-MS-MS method for the determination of nevirapine, a non-nucleoside reverse transcriptase inhibitor, in human plasma.}, author={Jingduan Chi and Anura L. Jayewardene and Judith A. Stone and Francesca T. Aweeka}, journal={Journal of pharmaceutical and biomedical analysis}, year={2003}, volume={31 5}, pages={953-9} }