An LC-MS/MS method for quantitation of cyanidin-3-O-glucoside in rat plasma: Application to a comparative pharmacokinetic study in normal and streptozotocin-induced diabetic rats.

@article{Yang2018AnLM,
  title={An LC-MS/MS method for quantitation of cyanidin-3-O-glucoside in rat plasma: Application to a comparative pharmacokinetic study in normal and streptozotocin-induced diabetic rats.},
  author={Chunxia Yang and Qiuhua Wang and Shenbao Yang and Qiong Yang and Ying Wei},
  journal={Biomedical chromatography : BMC},
  year={2018},
  volume={32 2}
}
A sensitive and reliable liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed to determine cyanidin-3-O-glucoside (Cy-3G) in normal and streptozotocin-induced diabetic rat plasma. Chromatographic separation was carried out on a Zorbax SB-C18 (50 × 4.6 mm, 5 μm) column and mass spectrometric analysis was performed using a Thermo… CONTINUE READING