An Italian cost-effectiveness analysis of paclitaxel albumin (nab-paclitaxel) versus conventional paclitaxel for metastatic breast cancer patients: the COSTANza study

  title={An Italian cost-effectiveness analysis of paclitaxel albumin (nab-paclitaxel) versus conventional paclitaxel for metastatic breast cancer patients: the COSTANza study},
  author={Carlo Lazzaro and Roberto Bordonaro and Francesco Cognetti and Alessandra Fabi and Sabino De Placido and Grazia Arpino and Paolo Marchetti and Andrea Botticelli and Paolo Pronzato and Elisa Martelli},
  booktitle={ClinicoEconomics and outcomes research : CEOR},
PURPOSE Paclitaxel albumin (nab-paclitaxel) is a nanoparticle albumin-bound paclitaxel formulation aimed at increasing therapeutic index in metastatic breast cancer. When compared to conventional paclitaxel, nab-paclitaxel has a reported longer time to progression, higher response, lower incidence of neutropenia, no need for premedication, shorter time of administration, and in pretreated metastatic breast cancer patients, extended overall survival. This study investigates the cost… CONTINUE READING


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